Selank 10mg Research Peptide for Laboratory Use

Product Details and Specifications for This Research Peptide

Each Selank 10 mg vial contains only the peptide as a dry powder, with no water, solvent, filler or other active ingredient. It is a single compound, not a blend, so any result in your experiment can be attributed to Selank alone. Several related Selank peptides are sold under similar names, including N-acetyl Selank and Selank combined with Semax; this vial is the standard, unmodified sequence.

How Is It Studied in Laboratory Research?

What does Selank do in the lab, and how does Selank work? Its mechanism is not fully understood. Published work, mostly from Russian groups linked to its developers, has studied peptides Selank is often grouped with (Semax and tuftsin) in four areas: the GABA system, brain signalling and gene expression in rodents, enkephalin and immune signalling, and a small number of clinical studies in Russia. What is Selank peptide used for outside Russia? As a research tool only. The findings below come mainly from rodent and laboratory experiments and do not show any effect in people.

GABA and Inhibitory Neurotransmission Research

GABA (gamma-aminobutyric acid) is the brain’s main inhibitory messenger. It mostly works through GABA-A receptors, the same receptors that benzodiazepines act on. Most interest in Selank GABA research comes from two kinds of study:

• Gene expression: Volkova et al. (2016) gave rats a single dose of Selank or GABA and measured 84 genes linked to GABA signalling in the frontal cortex, one and three hours later. Selank changed the expression of a number of these genes, and at one hour the pattern of changes was strongly correlated with the pattern caused by GABA itself (r = 0.86).
• Receptor binding: an earlier binding study reported that Selank changed the number of GABA binding sites in rat brain tissue without changing how tightly the receptors bind GABA [VERIFY: V’yunova et al. 2014]. This is why some authors suggest Selank may act as an allosteric modulator, changing how the receptor responds rather than binding where GABA does.

Both findings come from rats. The authors describe a GABA-A mechanism as a hypothesis, not a proven one, and the gene studies measured messenger RNA, not receptor function.

Neuroplasticity and Brain Signalling Research in Animal Models

Neuroplasticity is the brain’s ability to change its connections, and one of the main signalling proteins involved is BDNF (brain-derived neurotrophic factor). A 2008 rat study reported that Selank changed BDNF expression in the hippocampus, a brain region involved in learning and memory [VERIFY: authors and detail, Dokl Biol Sci 2008]. Other rodent work from the same research network has looked at:

• learning and memory tasks in rats [VERIFY: source];
• changes in serotonin and other monoamine metabolism in brain tissue [VERIFY: source];
• wider gene expression changes (transcriptome studies) in rat brain tissue after a single dose.

These are animal findings. Most of them come from a small number of laboratories, and few have been independently repeated outside Russia.

Immune Signalling and Enkephalin Research in Cell Models

Because Selank is built on tuftsin, a peptide from the immune system, part of its research looks at immune and peptide signalling outside the brain:

• Enkephalin breakdown: enkephalins are short opioid-like peptides made by the body, and they are broken down quickly by enzymes in blood. Kost et al. (2001) found in a test tube that Selank inhibited the enkephalin-degrading enzymes in human serum, with half the activity blocked at about 20 µM (Semax: about 10 µM). Five-amino-acid fragments of the peptides were also active; shorter fragments were not.
• Inflammation-related genes: Kolomin et al. (2011) measured inflammation-related gene expression in mouse spleen after Selank administration and reported changes in a number of cytokine and chemokine genes [VERIFY: genes and direction].
• Antiviral activity: Selank has been tested against influenza virus in cell cultures and mice [VERIFY: Ershov et al. 2009].

What Does Current Evidence Say About Human Studies?

Does Selank work in people? The evidence available cannot answer that with confidence. There are a few small clinical studies from Russia, published mainly in Russian, by groups linked to its developers. The best known, Zozulia et al. (2008), compared Selank with the benzodiazepine medazepam in 62 patients with generalized anxiety disorder or neurasthenia, without blinding or a placebo group [VERIFY: design details]. Another study measured immune markers such as interleukin-6 in patients (Uchakina et al. 2008), and later studies combined Selank with phenazepam [VERIFY]. There are no large, independent, placebo-controlled trials, and none published in English-language journals that we could find [CHECK clinicaltrials.gov before publishing]. Selank is not an approved medicine in the UK, and no safe or effective use in people has been established outside its Russian registration. Genesis Peptides makes no health claims for this product.

Selank vs Semax: What Is the Difference in Research?

Selank and Semax are the two best-known Russian-developed research peptides, and Selank vs Semax is one of the most common comparisons. They come from the same institute and share the Pro-Gly-Pro tail, but they are built on different natural molecules.

The main Semax vs Selank difference is the parent molecule: Selank comes from an immune peptide, Semax from a hormone fragment, and their research has followed those origins. On Selank peptide vs Semax in the lab, the two are often studied side by side, and some suppliers sell Selank and Semax peptides as a blend. A blend makes it impossible to tell which peptide caused a result, so many study designs use separate products. On a COA, the masses tell them apart: about 751.9 for Selank, about 813.9 for Semax. [LINK: Semax nasal spray]

Certificate of Analysis and Purity Testing for Each Batch

Every batch of our Selank peptide comes with a certificate of analysis (COA) from [CONFIRM: lab name] [independent third-party lab: CONFIRM]. The COA shows two separate tests: HPLC, which measures purity, and mass spectrometry, which confirms the molecule. Both are needed. A high purity figure alone does not prove the main peak is Selank, and a correct mass alone does not show how much of the sample is impurity.

How to Find and Download the Certificate for Your Batch

1. Find the batch number on your vial label [and on the packing slip: CONFIRM].
2. Go to [LINK: COA library page], or use the COA link in the product images on this page.
3. Choose the certificate whose batch number matches your vial and download the PDF.
4. If you cannot find your batch, contact us at [CONFIRM: email] and we will send it.

How to Read HPLC Purity and Mass Spectrometry Results

• HPLC purity: the trace shows one main peak for Selank and smaller peaks for impurities, such as shorter “deletion” sequences missing one amino acid. Purity is the main peak’s area as a percentage of all peaks. This batch: [CONFIRM: __%].
• Mass spectrometry: the measured monoisotopic mass should be about 751.4. It is usually reported as [M+H]+ at about 752.4, and often as [M+2H]2+ at about 376.7, because the lysine and arginine side chains pick up protons easily. A mass of about 813.9 would mean Semax, not Selank.
• Net peptide content (if shown): the share of the powder that is peptide, as opposed to counter-ions (usually acetate) and residual water. Net peptide content is usually well below 100% even when purity is high.
• Check the details: the product name, batch number, test date and lab name should all be on the certificate.

How to Store and Handle a Lyophilised Peptide Vial

Does Selank need to be refrigerated? As a dry, lyophilised powder it is much more stable than in solution, but it should still be kept cold. For long-term storage, keep the sealed vial at −20 °C, away from light and moisture. For short periods, 2–8 °C in a fridge is generally suitable for lyophilised peptides [CONFIRM in-house guidance]. Short periods at room temperature during delivery are normal. Before opening a cold vial, let it reach room temperature so moisture from the air does not condense on the powder. Handle with gloves, using sterile technique, in a lab setting.

Storage Before and After Reconstitution

• Before reconstitution: sealed vial at −20 °C long term, or 2–8 °C short term. How long does Selank last unopened? [__ months: CONFIRM], and never past the expiry date on the label.
• Selank 10mg reconstitution: Selank dissolves readily in water. In research protocols, the powder is usually dissolved in sterile bacteriostatic water [LINK: bac water], added slowly down the side of the vial and swirled gently rather than shaken. The volume used depends on the concentration your protocol needs.
• After reconstitution: store the solution at 2–8 °C, protected from light, and use within [__ days/weeks: CONFIRM from your stability data]. Avoid repeated freezing and thawing; if longer storage is needed, split the solution into single-use aliquots and freeze them.
• Discard any solution that turns cloudy, changes colour or contains particles.

Is Research Use of This Peptide Legal in the UK, and Is It Banned in Sport?

[LEGAL REVIEW: this section]

People often ask “Is Selank legal?” These are the facts we can state; they are not legal advice.

• Not a controlled drug. Selank is not listed under the Misuse of Drugs Act 1971 [VERIFY].
• Not a licensed medicine in the UK. Selank has no marketing authorisation from the MHRA, so it cannot legally be sold or supplied in the UK as a medicine for human use, or as a food supplement. Is Selank FDA approved? No. It is not approved by the FDA in the US or the EMA in the EU. It is registered as a medicine only in Russia.
• Psychoactive Substances Act 2016. Because Selank acts on the nervous system in research models, supplying it for human consumption could fall under this Act. Supply as a research chemical, labelled and sold for laboratory use and not for consumption, is the basis on which we sell it [LEGAL REVIEW]. We will not sell to anyone who says they intend to use it on a person or an animal.

So is Selank legal to buy in the UK? For laboratory research, on the basis above [LEGAL REVIEW]. The rules depend on how a product is sold and used, and they can change. Our Selank UK stock is sold for research only.

Is it banned in sport? Selank is not named on the World Anti-Doping Agency (WADA) 2026 Prohibited List. Section S0 bans pharmacological substances not covered by another section that have no current approval for human therapeutic use by any government health authority. Because Selank is approved in Russia, whether S0 applies is not clear-cut. Athletes covered by UK Anti-Doping (UKAD) rules should check with UKAD before any contact with it [VERIFY with UKAD].

What to Check Before Buying Research Peptides in the UK

Before you buy Selank or any other research peptide, check:

• A batch-matched COA with both HPLC purity and mass spectrometry identity, from a named lab. For Selank, the mass should be about 751.9.
• The exact compound. The listing should say Selank (TKPRPGP), the amount per vial, and whether it is the standard sequence, N-acetyl Selank or a blend with Semax.
• Net peptide content and salt form, so you know how much actual peptide is in the vial.
• Clear research-use labelling and no dosing, mood, sleep or treatment claims. Many Selank for sale listings make these claims; a supplier that does is selling outside the rules.
• A UK address and contact details, and dispatch from the UK.
• Correct format: lyophilised powder in a sealed glass vial. Capsule products sold as “Selank” are not research materials and are rarely batch-tested in the same way.

The lowest Selank price is rarely the best value if there is no batch certificate behind it. Whoever you buy Selank peptide from, check the COA before you open the vial. Our Selank peptide for sale here is the 10mg vial: to order, add it to your basket at the top of this page [CONFIRM: or: “Selank buy button” wording to match your theme].

UK Delivery, Dispatch and Packaging

• Dispatch: orders placed before [CONFIRM: time] on a working day are dispatched the same day from [CONFIRM: town/county].
• Delivery: [CONFIRM: carrier and service, e.g. Royal Mail Tracked 24], [CONFIRM: price / free over £__].
• Packaging: vials are sealed and packed in [CONFIRM: protective packaging details], in plain outer packaging. Lyophilised peptides are stable at room temperature for the length of normal UK transit; store them as described above on arrival [CONFIRM].
• Payment: [CONFIRM: payment methods].

When you buy Selank UK stock from us, it is held and shipped within the UK, so there are no customs delays. Every Selank buy UK order includes the batch number on the packing slip for COA lookup, and our Selank peptide UK stock is batch-tested before it goes on sale. For larger lab orders, contact [CONFIRM: email].

What Is Selank and How Is It Related to Tuftsin?

What is Selank? It is a synthetic seven-amino-acid peptide developed by the Institute of Molecular Genetics of the Russian Academy of Sciences, working with the V.V. Zakusov Research Institute of Pharmacology in Moscow. The same institute developed Semax. In Russia, Selank is registered as a prescription medicine in nasal-drop form [VERIFY: registered 2009]. It is not licensed by the MHRA in the UK, the EMA in the EU or the FDA in the US, and outside Russia it is supplied only as a research chemical.

What is Selank peptide built from? Its first four amino acids, Thr-Lys-Pro-Arg, are tuftsin. Tuftsin is a natural tetrapeptide released from the Fc part of the heavy chain of immunoglobulin G (IgG), residues 289 to 292, and was first described in 1970 as a peptide that stimulates phagocytosis, the process by which immune cells engulf particles [VERIFY: Najjar & Nishioka 1970]. Tuftsin on its own is broken down within minutes by enzymes in blood. The developers added a Pro-Gly-Pro tail to make the chain more resistant to those enzymes, which is the same stabilising tail used in Semax. That is how Selank is related to tuftsin: it is tuftsin with a three-amino-acid extension. Encyclopaedia summaries such as the Selank wiki entry describe it the same way.

Selank or N-acetyl Selank? Searches for N-acetyl Selank, acetyl Selank, Selank N-acetyl or NA-Selank refer to a modified version with an acetyl group added to the first amino acid. N acetyl Selank amidate (or Selank amidate) usually also has the C-terminal acid replaced by an amide. Both changes are common in peptide chemistry to slow breakdown by enzymes, but there is very little peer-reviewed research on N acetyl Selank peptide, and its structure varies between suppliers. On N-acetyl Selank vs Selank (or NA-Selank vs Selank): almost all published Selank research uses the unmodified sequence, which is what this vial contains. If you are deciding on Selank or N acetyl Selank for a study, the standard form has far more literature to compare your results with.

Amino Acid Sequence, Molecular Weight and Chemical Structure

• Sequence: H-Thr-Lys-Pro-Arg-Pro-Gly-Pro-OH (one-letter code TKPRPGP). Positions 1 to 4 are tuftsin; positions 5 to 7 (Pro-Gly-Pro) are the stabilising tail.
• Formula and weight: C33H57N11O9, average molecular weight about 751.9 g/mol, monoisotopic mass about 751.43.
• CAS number: 129954-34-3.
• Structure: three of the seven residues are proline, whose ring-shaped side chain makes the backbone rigid at those points and makes the chain harder for many peptidases to cut. Lysine and arginine have long side chains that are positively charged at neutral pH, so with the free N-terminal amine and the C-terminal acid, Selank carries a net charge of about +2 at neutral pH and dissolves readily in water.
• Stability in biological samples: the half-life of Selank in blood is short. Rodent studies report it is broken down within minutes [VERIFY: figure and source], and published Selank half-life values vary with species and method, so check primary sources for your model.

Scientific References and Published Studies

Key published studies on Selank and tuftsin cited on this page:

1. Najjar VA, Nishioka K. “Tuftsin”: a natural phagocytosis stimulating peptide. Nature. 1970;228(5272):672–673. [VERIFY]
2. Kost NV, Sokolov OYu, Gabaeva MV, Grivennikov IA, Andreeva LA, Myasoedov NF, Zozulya AA. Semax and selank inhibit the enkephalin-degrading enzymes from human serum. Bioorg Khim. 2001;27(3):180–183. doi:10.1023/a:1011373002885
3. Zozulia AA, Neznamov GG, Siuniakov TS, et al. Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia. Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(4):38–48. PMID 18454096 [VERIFY pages]
4. Uchakina ON, Uchakin PN, Miasoedov NF, et al. Immunomodulatory effects of selank in patients with anxiety-asthenic disorders. Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(5):71–75. PMID 18577961 [VERIFY pages]
5. Intranasal administration of the peptide Selank regulates BDNF expression in the rat hippocampus in vivo. Dokl Biol Sci. 2008. PMID 18841804 [VERIFY authors, volume, pages]
6. Kolomin TA, Shadrina MI, Andreeva LA, et al. Expression of inflammation-related genes in mouse spleen under tuftsin analog Selank. Regul Pept. 2011. PMID 21609736 [VERIFY volume, pages]
7. Volkova A, Shadrina M, Kolomin T, Andreeva L, Limborska S, Myasoedov N, Slominsky P. Selank administration affects the expression of some genes involved in GABAergic neurotransmission. Front Pharmacol. 2016;7:31. doi:10.3389/fphar.2016.00031
8. World Anti-Doping Agency. Prohibited List 2026, S0 Non-Approved Substances.

[CHECK: add DOI or PubMed links before publishing; add the V’yunova 2014 binding study and Ershov 2009 influenza study if you keep those sentences]

Related Research Peptides and Buying Guides

Selank is often researched alongside other Russian-developed peptides, and in other formats. Related products:

• Selank nasal spray 10mg: the same peptide as a ready-made solution with a metered pump, for intranasal study designs. [LINK: Selank nasal spray]
• Semax nasal spray 10mg: the ACTH(4-7)-based peptide from the same institute, the usual comparison for Selank. [LINK: Semax nasal spray]
• Epitalon 10mg vial: another short peptide first developed in Russia, as a lyophilised research vial. [LINK: Epitalon vial]
• Bacteriostatic water 10ml: for reconstituting lyophilised peptides in research protocols. [LINK: Bac water]
• Guides: [LINK: How to read a peptide COA] · [LINK: How to store research peptides]

Or return to the top of this page to order Selank 10mg.

All products are for laboratory research use only. Not for human or veterinary use.